[4 credit(s)] Techniques of immunoassays and techniques of isolation, manipulation, and analysis of proteins/nucleic acids are covered. Includes both lecture and laboratory.
[6 credit(s)] Prerequisite: Approval of the Director of Clinical Chemistry. Students rotate through the clinical laboratory at Cleveland medical centers, being trained in instrumentation, quality control, and diagnostic uses of various testing methodologies. Students are assigned evaluations and/or development projects for a more in-depth experience. Management issues of the clinical laboratory also are addressed. Offered in the summer to clinical chemistry majors only.
[4 credit(s)] Prerequisites: Undergraduate organic chemistry, physical or analytical chemistry or prior permission of the Faculty instructor. Survey of basic and advanced analytical techniques that are critical in investigations of structure and dynamics of biomolecules, including protein, DNA and RNA folding and structures and function. Examination of biomolecules using basic and ADVANCED techniques including spectroscopic, time-resolved, and molecular imaging techniques.
[1-11 credit(s)] Prerequisite: Approval of advisor. An advanced laboratory program in selected techniques to be determined by the needs and interests of the student. Offered every semester.
[1 credit(s)] Prerequisite: Departmental Approval. Written report and oral presentation of research progress to student’s Research Advisor and Thesis/Dissertation Committee; includes submission of figures and data, and receiving feedback from the Advisor and the Committee.
[1 credit(s)] Prerequisites: Graduate standing, completion of at least one full-time academic year in the Chemistry MS program or in the Clinical-Bioanalytical Chemistry PhD program, and permission of advisor. Provides students with practical experience in chemical and its applied fields. Students are required to submit a final project report and make an oral presentation at the end of the course. May be repeated one time for credit. Graded on an S/U basis.
[1 credit(s)] Introduction to effective collection, organization, and presentation of technical information. Students are required to present seminars, preferably dealing with some aspect of their proposed research program.
[1-16 credit(s)] Prerequisite: Departmental approval. Methods and techniques of experimental research under the direction of a faculty advisor; includes submission of an acceptable thesis. Offered every semester.
[1 credit(s)] Prerequisite: Approval of instructor. Orientation to the philosophy and methods used in teaching chemistry; observation and directed practice teaching in the laboratory and classroom.
CHM 704 - Special Topics In Environmental Chemistry
[3 credit(s)] Prerequisites: CHM 504 and approval of advisor. Discussion of special topics in environmental chemistry, reflecting student and faculty interests.
[3 credit(s)] Prerequisite: Approval of advisor. Discussion of special topics in analytical chemistry, reflecting student and faculty interests. May be repeated for credit with change of topic.
[3 credit(s)] Prerequisite: CHM 511 or equivalent. Theoretical principles of analytical chemistry, including equilibrium, error analysis, and quantitative calculations.
[4 credit(s)] Prerequisite: CHM 511 or prior approval of the Faculty instructor. Theory, principles, and applications of electroanalytical chemistry. Electron transfer in molecular mechanisms and molecular imaging, sensors, and state-of-the-art devices for analysis and diagnosis. Theory and application of advanced scanning probe techniques including AFM, STM, Scanning Electrochemical Microscopy (SECM), and coupled AFM-electrochemical analysis.
[4 credit(s)] Prerequisite: CHM 511 or equivalent. Comprehensive survey of separation techniques, including solvent extraction, gas chromatography, liquid chromatography, supercritical fluid chromatography, chromatography detectors, gel electrophoresis, and capillary electrophoresis.
[3 credit(s)] Prerequisite: Approval of advisor. This course covers electrospray, MALDI, CI, APCI, EI, and other novel ionization methods, as well as quadruple, TOF, FTMS, and double sector mass spectrometry. GC/MS and LC/MC also are discussed.
[4 credit(s)] Prerequisite: Approval of Advisor or one year of undergraduate physical chemistry. Principles of quantum theory including aspects of structure and spectroscopy. Will include projects using common quantum computational software programs.
[4 credit(s)] Prerequisite: CHM 631/731 or approval of instructor. Discussion of special topics in organic chemistry reflecting student and faculty interests.
[4 credit(s)] Prerequisite: CHM 332 or equivalent. Structure and properties of organic compounds, including stereochemistry, conformational analysis, aromaticity, reactions, and reaction intermediates.
[4 credit(s)] Prerequisite: CHM 731. A study of the mechanisms of organic reactions and their implications in synthetic and structural organic chemistry.
[4 credit(s)] Prerequisite: Approval of advisor. Discussion of special topics in inorganic chemistry, reflecting student and faculty interests. Currently, bioinorganic chemistry and inorganic nanotechnology are the modern topics. Examples from the newest chemical literature will be discussed.
[4 credit(s)] Prerequisite: CHM 441 or equivalent. Application of chemical kinetics, thermodynamics, and elementary quantum chemistry to the determination of mechanisms of inorganic reactions; structural aspects of inorganic reactivities. Introduction to bioinorganic chemistry. Applications cover almost every element and examples from the newest chemical literature.
[4 credit(s)] Prerequisite: CHM 625/725 or equivalent. Symmetry and group theory of inorganic and organometallic compounds; irreducible representations and character tables; applications to valence-bond and molecular-orbital theories of chemical bonding, structures, and spectroscopy. Applications cover examples from the newest chemical literature.
[1 credit(s)] Prerequisite: Approval of advisor. Discussion of special topics in clinical chemistry and related clinical disciplines. May be repeated for credit with change of topic.
[4 credit(s)] Laboratory diagnosis of kidney, liver, and hemolytic diseases. Instruction includes physiology and pathophysiology in conjunction with laboratory testing for the above diseases. Laboratory statistics also are covered.
[4 credit(s)] Laboratory investigations of disorders in acid-base balance, lipid and carbohydrate metabolism, and endocrine functions. Biochemical markers of myocardial infarction. Case studies.
[4 credit(s)] Prerequisite: CHM 332 or CHM 402. Chemistry of proteins, carbohydrates, and lipids; immunology and AIDS. Enzyme and energetics of metabolic reactions.
[4 credit(s)] Prerequisite: CHM 653/753. Metabolism of nitrogen-containing compounds, vertebrate metabolism, neurotransmission, nucleotides, and nucleic acids, DNA processes, RNA synthesis and processing, protein synthesis, gene expression, and cancer.
[4 credit(s)] Techniques of immunoassays and techniques of isolation, manipulation, and analysis of proteins/nucleic acids are covered. Includes both lecture and laboratory.
[6 credit(s)] Prerequisite: Approval of the Director of Clinical Chemistry. Students rotate through the clinical laboratory at Cleveland medical centers, being trained in instrumentation, quality control, and diagnostic uses of various testing methodologies. Students are assigned evaluations and/or development projects for a more in-depth experience. Management issues of the clinical laboratory also are addressed. Offered in the summer to clinical chemistry majors only.
[11 credit(s)] Prerequisite: Approval of the Director of Clinical Chemistry. Students rotate through instrumentation stations not covered in the first internship course (CHM 656/756) in the clinical laboratory at The Cleveland Clinic Foundation or other medical facility. Topic areas are the same as described for CHM 656/756. Offered in the summer to clinical chemistry majors only.
[1 credit(s)] Tutorial and student participation program emphasizing current developments in various facets of clinical chemistry. Open only to clinical chemistry majors.
[4 credit(s)] Prerequisites: Undergraduate organic chemistry, physical or analytical chemistry or prior permission of the Faculty instructor. Survey of basic and advanced analytical techniques that are critical in investigations of structure and dynamics of biomolecules, including protein, DNA and RNA folding and structures and function. Examination of biomolecules using basic and ADVANCED techniques including spectroscopic, time-resolved, and molecular imaging techniques.
[1-11 credit(s)] Prerequisite: Approval of advisor. An advanced laboratory program in selected techniques to be determined by the needs and interests of the student. Offered every semester.
[1 credit(s)] Prerequisite: Departmental Approval. Written report and oral presentation of research progress to student’s Research Advisor and Thesis/Dissertation Committee; includes submission of figures and data, and receiveing feedback from the Advisor and the Committee.
[1 credit(s)] Prerequisites: Graduate standing, completion of at least one full-time academic year in the Chemistry MS program or in the Clinical-Bioanalytical Chemistry PhD program, and permission of advisor. Provides students with practical experience in chemical and its applied fields. Students are required to submit a final project report and make an oral presentation at the end of the course. May be repeated one time for credit. Graded on an S/U basis.
[1 credit(s)] Introduction to effective collection, organization, and presentation of technical information. Students are required to present seminars, preferably dealing with some aspect of their proposed research program.
[1-16 credit(s)] Prerequisite: Departmental approval. Doctoral research under the direction of a faculty advisor; includes submission of an acceptable dissertation. Offered every semester.
CVE 500 - Mathematical Methods In Engineering Mechanics
[4 credit(s)] Partial differential equations, integral equations, complex variables, integral transforms, and variational calculus as applied to the areas of elasticity, plasticity, fracture mechanics, materials science, and structural engineering.
[4 credit(s)] Includes a basic review of probability and statistics. Aspects of Monte Carlo simulation are discussed as it relates to reliability analysis and parameter estimation. Concepts of Weibull analysis and weakest link theory will be thoroughly discussed along with other system reliability topics. Standard techniques to estimate statistical parameters are presented. Limit state functions, the reliability index, and approximate methods are discussed. Code provisions based on probabilistic methods will be presented.
[3 credit(s)] Energy methods approach to matrix structural analysis, including the development of element material stiffness, geometric stiffness, and mass matrices of basic structural elements; emphasis on the displacement method with computer program solutions of truss and frame problems.
[4 credit(s)] Techniques in the formulation and application of the Finite Element method. Calculus of variation, potential energy and Galerkin formulations of element stiffness equations. Uniaxial, biaxial element, Isoparametric element formulations. Applications to plane stress, plane strain, and axisymmetric problems; solutions of engineering problems using computer software.
[4 credit(s)] Prerequisite: ESC 211. This course fosters an understanding of a number of advanced concepts in the field of engineering mechanics. Topics include three-dimensional stress-strain relationships, including failure theories; bending of non-symmetrical members; curved beam theory; beams on elastic foundations; torsion of non-circular shafts using the membrane analogy; and plate theory.
[3 credit(s)] Prerequisite: CVE 422. Properties of hydraulic cements, aggregates, plastic, and hardened concrete; effect of admixtures and curing conditions; specifications and acceptance tests; placement, consolidation, finishing, and durability of concrete.
[3 credit(s)] Prerequisite: CVE 422. Immediate and long-term stress losses in post-tensioned and pre-tensioned members; analysis and design of post-tensioned and pre-tensioned members for flexure and shear; proportioning of members, calculation of the amount, and positioning of reinforcement.
[4 credit(s)] Methods of nondestructive evaluation are studied. Topics include ultrasonics, acoustic emissions, penetrants, eddy current, X-ray and neutron radiography, digital radiography, computed tomography, and thermography. Cross-listed with MME 524.
[4 credit(s)] Vertical dead and live loads due to gravity, roof, and floor. Lateral design loads due to wind and seismic. Properties and grades of sawn lumber and glulam members, modification factors of allowable stresses; analysis and design of axially loaded members, combined axial and bending effects. Properties and grades of plywood and other rated sheathing; analysis and design of horizontal diaphragms, chords, drag struts, and shearwalls. Design of nailed, bolted connections; timber connectors and connection hardware.
[3 credit(s)] Subsurface explorations; shallow foundations; design of spread footings, mats, retaining walls, and deep foundations; design of piles, piers, and caissons.
[4 credit(s)] Engineering classification of soils, clay mineralogy, properties of different types of soils, such as strength, permeability, volume-density characteristics; soil contaminant interaction, method of soil stabilization, method of soil decomposition, process selection, and site remediation. Soil decontamination design project.
[3 credit(s)] The Traffic Flow Theory course provides the basic concepts and theories of traffic flow characteristics and the associated analytical techniques. This course reviews the foundations of traffic science and presents the major classes of models derived for traffic flow. Recent developments and topics of current research are introduced. The course also addresses the implications of the models and the traffic system properties for traffic operations and control.
[3 credit(s)] Focus on factors involved in the process of urban planning and regional transportation systems, encompassing all modes. Provides students with theory and applications of urban transportation planning studies, traffic models, investment models, programming and scheduling.
[3 credit(s)] This course covers: Crashes, contributing factors, crash analysis and estimation methods, and the roadway safety management process including: network screening;diagnosis; selection of countermeasures; economic analysis; project prioritization; and safety effectiveness evaluation.
[3 credit(s)] Survey of transportation development, characteristics, and planning; traffic characteristics capacity of various systems, including basic procedures, controls, and criteria in highway design; environmental considerations.
[3 credit(s)] Properties of materials used in highway construction. Effects of loading and the environment on pavement life. Design of flexible and rigid pavement systems. Construction methods and management.
[3 credit(s)] Characterization and analysis of the hydrologic cycle and associated hydrologic abstractions. Statistical analysis of hydrologic events, hydrologic routing, and the effects of urbanization on the hydrologic response of a watershed.
[3 credit(s)] Application of the principles of the conservation of mass, energy, and momentum to open channel flow phenomena. Analysis of open channel hydraulic structures and floodplain hydraulics. Emphasis is on computer applications and numerical methods.
[3 credit(s)] Analysis and hydraulic design of water resource engineering subsystems, including subsurface drainage, pressure flow systems, pumps and turbines, reservoirs, spillways, and landfills.
[3 credit(s)] Analysis of the physical properties and the resultant groundwater flow in porous media. Application of the principles of the conservation of mass, energy, and momentum to groundwater flow systems. Includes well hydraulics, well design, aquifer analysis, infiltration, flow in the unsaturated zone, and introduction to groundwater contamination.
[3 credit(s)] Prerequisite: CVE 561. Numerical and statistical methods employed in computer models that simulate the movement of surface water through the hydrologic cycle. Emphasizes the utilization of computer programs to evaluate the hydrologic response of watersheds.
[1 credit(s)] Prerequisite: Graduate Standing. Provides students with experience and instruction on research and presentation methods and oral communication of technical information, focused on civil engineering issues. Invited experts from industry and academia, from various civil engineering field, present and discuss current issues and trends in research and professional practice. Students will present a research paper at the end of the course.
[1 credit(s)] Prerequisites: Graduate standing in Civil Engineering, completion of at least one full-time academic year in MSCE or Doctor of Philosophy in Engineering program, and permission of advisor. This internship provides students with practical experience in civil/environmental engineering. Students are required to submit a final project report and make a presentation at the end of the course. May be taken up to two times for credit.
[4 credit(s)] Prerequisite: CVE 513. Elasticity topics include tensor algebra, fundamentals of stress analysis, fundamentals of deformation theory, thermo-elastic constitutive relationships, uniqueness of solution, Airy’s stress function, and various solution techniques for two-dimensional problems.
[4 credit(s)] Prerequisite: CVE 512 or MCE 580. Advanced techniques in the formulation of the Finite Element with applications. Development of three dimensional elements, tetrahedrals and hexahedrals. Formulation of thin and moderately thick plate bending elements and shell elements. 3D isoparametric beam, plate and shell elements, solutions of engineering problems using computer software.
[3 credit(s)] Prerequisites: CVE 512 and/or permission of instructor. Isoparametric finite element discretization, incremental equations of motion. Total and updated Lagrangian formulations. Nonlinear geometry, nonlinear material problems in two and three dimensions. Computer solution of problems.
[3 credit(s)] Prerequisite: CVE 511. Euler buckling of bars, beam/columns, and plates using matrix methods; concepts of geometric nonlinearity, including bifurcation and limit point analysis using iterative numerical techniques; applications to load eccentricity and system imperfection.
CVE 620 - Fracture Mechanics and Plasticity Theory
[4 credit(s)] Prerequisite: CVE 604. The stress and deformation field in the region of a crack are derived using linear elastic analysis. Topics include analyzing the change in potential energy due to crack propagation (Griffith’s analysis), understanding the origin of critical fracture toughness parameters, and developing fundamental fracture criteria. In addition the course focuses on time-dependent plastic deformation analysis. Relationships between stress and strain that agree with experimental observations beyond the yield stress are constructed. Applications of these inelastic constitutive relationships in predicting plastic deformations in simple components are presented. Drucker’s stability postulates are discussed, and the principles of slip-line theory are given. General theorems of limit analysis and their application in structural analysis are highlighted. The J-integral and fundamentals of elastic-plastic fracture analysis are presented.
[2 credit(s)] Prerequisite: CVE 620. The fundamental concepts of crack growth in the presence of cyclic stress are considered. The fracture mechanics approach is adopted. Similitude concepts, common empirical and semi-empirical equations, variable amplitude loading, and rain-fall analysis are discussed.
[2 credit(s)] Prerequisite: CVE 604. Modeling of continua as a viscoelastic material in which stress and strain fields in deformable bodies are time and spatially dependent. Viscoelastic models include Maxwell fluids and Kelvin solids. Creep phenomena, stress relaxation, hereditary integrals, viscoelastic beams, beams on continuous supports, vibration, and wave propagation in viscoelastic materials are studied.
[3 credit(s)] Prerequisite: CVE 561. Numerical and statistical methods employed in computer models that simulate the movement of surface water through the hydrologic cycle. Emphasizes the utilization of computer programs to evaluate the hydrologic response of watersheds.
[1 credit(s)] Prerequisite: Graduate Standing. Provides students with experience and instruction on research and presentation methods and oral communication of technical information, focused on civil engineering issues. Invited experts from industry and academia, from various civil engineering field, present and discuss current issues and trends in research and professional practice. Students will present a research paper at the end of the course.
[4 credit(s)] Prerequisite: CVE 513. Elasticity topics include tensor algebra, fundamentals of stress analysis, fundamentals of deformation theory, thermo-elastic constitutive relationships, uniqueness of solution, Airy’s stress function, and various solution techniques for two-dimensional problems.
[3 credit(s)] Prerequisite: CVE 604 or permission of instructor. Development of the principles of virtual work, total potential energy, complementary virtual work, total complementary energy, and Reissner’s principle for solid mechanics problems. Castigliano theorems, Ritz, Galerkin, and finite element methods. Applications in structural mechanics problems for bars, beams, columns, plates, and shells. Offered on sufficient demand.
[3 credit(s)] Prerequisite: CVE 512. Extension of the finite element method to the solution of advanced three-dimensional stress analysis problems. Offered on sufficient demand.
[3 credit(s)] Prerequisites: CVE 512 and/or permission of instructor. Isoparametric finite element discretization and incremental equations of motion. Total and updated Lagrangian formulations. Nonlinear geometry and nonlinear material problems in two- and three-dimensions. Computer solution of problems. Offered on sufficient demand.
[3 credit(s)] Prerequisite: CVE 511. Euler buckling of bars, beam/columns, and plates using matrix methods; concepts of geometric nonlinearity, including bifurcation and limit point analysis using iterative numerical techniques; applications to load eccentricity and system imperfection.
CVE 720 - Fracture Mechanics and Plasticity Theory
[4 credit(s)] Prerequisite: CVE 604. The stress and deformation field in the region of a crack are derived using linear elastic analysis. Topics include analyzing the change in potential energy due to crack propagation (Griffith’s analysis), understanding the origin of critical fracture toughness parameters, and developing fundamental fracture criteria. In addition, the course focuses on time-dependent plastic deformation analysis. Relationships between stress and strain that agree with experimental observations beyond the yield stress are constructed . Other highlighted topics include the application of these inelastic constitutive relationships in predicting plastic deformations in simple components; Drucker’s stability postulates; the principles of slip-line theory; general theorems of limit analysis and their application in structural analysis; and the J-integral and fundamentals of elastic-plastic fracture analysis.
[2 credit(s)] Prerequisite: CVE 620. The fundamental concepts of crack growth in the presence of cyclic stress are considered. The fracture mechanics approach is adopted. Similitude concepts, common empirical and semi-empirical equations, variable amplitude loading, and rain fall analysis are discussed.
[2 credit(s)] Prerequisite: CVE 604. Modeling of continua as a viscoelastic material where stress and strain fields in deformable bodies are time and spatially dependent. Viscoelastic models include Maxwell fluids and Kelvin solids. Creep phenomena, stress relaxation, hereditary integrals, viscoelastic beams, beams on continuous supports, vibration, and wave propagation in viscoelastic materials are studied.
[1-16 credit(s)] Prerequisite: Standing in Engineering Doctoral Program. Up to 10 credits may be used toward the dissertation credit requirements. Available every semester.
[1-16 credit(s)] Prerequisite: Successful completion of candidacy examination and Dissertation Proposal Approval Form on file with the College of Graduate Studies. A design project or a research problem under the guidance of a faculty member, culminating in the writing of a dissertation. Available every semester.
[3 credit(s)] Introduction to the history of science, communication theories, and the nature of scientific inquiry. Focuses on a survey of major theories, the logic of communication inquiry, techniques in literature search and review, and the skills in critiquing research. Also examines the structure and logic of the scientific method, as well as different research methodologies and when they are employed. Introduces students to key principles of design, sampling, reliability and validity, measurement, and hypothesis testing.
[3 credit(s)] Examines specific quantitative and qualitative research methods, including survey, experimental, and observational designs. Emphasis is on design and execution of research for exploratory, descriptive, and explanatory purposes. Students also learn statistical procedures employed in analyzing data through an introduction to multivariate statistics and an overview of t-tests, analysis of variance, and multiple regression techniques.
[3 credit(s)] The examination of the structure, assumptions, and testing of various theories in the physical and social sciences. This course will examine their application to communication science as well as theory construction techniques.
COM 544 - Mediation and Collaborative Problem Solving
[3 credit(s)] Examines how mediation works, factors that determine whether mediation can be used to resolve disputes, and the conditions under which mediation is most effective.
[3 credit(s)] Focuses on the structure, functions, and processes of organizational teams and work groups. Special attention is given to promoting effective teamwork in today’s organizations through methods of team building and examining leadership issues confronting teams.
[3 credit(s)] Focuses on interactions of people involved in the health care process and the dissemination and interpretation of health-related messages. Emphasis is on provider-recipient communication, communication in health concerns as they relate to physical, mental, and social health issues.
[3 credit(s)] Prerequisites: COM 501 & COM 512; or permission of the Graduate Director. Introduces students to the fundamentals of communication campaigns, including public information and political campaigns. Course content encompasses the role of campaigns in shaping social, cultural, and political agendas; theoretical foundations of communication campaigns; and campaign management techniques. Students participate in an actual campaign exercise to gain experience as campaign strategists. Students do analysis of Social Marketing Campaign(s) from literature.
[3 credit(s)] Prerequisites: Graduate Standing in Applied Communication Theory & Methodology or permission of instructor. This course emphasizes practical aspects of promotional communication. It examines the process by which media messages are evaluated in various media environments with an emphasis on social media. The course will explore key social media metrics and analytics to allow students to track digital and social media content. Students will learn how to evaluate a social media campaign’s success. The course will also introduce user experience concepts and measurement tools.
COM 595 - Special Topics in Communication Theory & Methodology
[3 credit(s)] In-depth research in a specific topic in communication theory and methodology. Topics to be announced. May be repeated to a maximum of 6 hours provided no topic is repeated.